IFNL3 genotype is associated with pulmonary fibrosis in patients with systemic sclerosis
نویسندگان
چکیده
منابع مشابه
Carbonylated proteins in bronchoalveolar lavage of patients with sarcoidosis, pulmonary fibrosis associated with systemic sclerosis and idiopathic pulmonary fibrosis.
Oxygen-derived free radicals produced by phagocytes have been postulated to contribute to lung tissue damage occurring during diffuse lung diseases (DLD). The two-dimensional electrophoretic (2-DE) analysis of bronchoalveolar lavage (BAL) protein composition revealed different protein profiles in sarcoidosis (S), idiopathic pulmonary fibrosis (IPF) and systemic sclerosis (SSc) with a significan...
متن کاملIFNL3 genotype is associated with differential induction of IFNL3 in primary human hepatocytes.
BACKGROUND Lambda interferons (IFNLs) have potent antiviral activity against HCV, and polymorphisms within the IFNL gene cluster near the IFNL3 gene strongly predict spontaneous- and treatment-related HCV infection outcomes. The mechanism(s) linking IFNL polymorphisms and HCV control is currently elusive. METHODS IFNL induction was studied in primary human hepatocytes (PHH) from 18 human dono...
متن کاملthe past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
Thrombin-mediated cellular events in pulmonary fibrosis associated with systemic sclerosis (scleroderma).
The vascular hypothesis for the pathogenesis of systemic sclerosis was perhaps Professor LeRoy's most important scientific contribution. One early and important consequence of vascular injury is the release of activated thrombin. In this manuscript we present our data and review the current understanding of the role played by thrombin in the process of fibrosis, particularly as it relates to sc...
متن کاملAntinuclear antibodies associated with pulmonary involvement in systemic sclerosis.
In response to Dr. Homasson, my comments are as follows: 1) Mv paper is about a personal experience with laser bronchoscopy Ofll\ 2) In the introductii)n, I mentioned a statenient by Dr. Shapshav drawn from reference 1 of my paper. 3) I have flO personal experience with that technique and therefore I am unable to judge Dr. Honiasson’s letter. I think Dr. Shapshay or Dr. Sanderson, who initiated...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-50709-9